Acomplia(
Generic Acomplia)
What
is Acomplia?
Obesity
is the result of excessive intake of food which later is accumulated
in the body beneath the skin in the form of fat, giving the body a bulky
look. Our neurological system has a control over our dietary habits.
Before eating anything we get permission from our brain. The brain permits
us only when it will have the signal of hunger sent to it by the cells
of the body. A neuro-receptor named as endo-cannabinoid-1 (CB-1) sends
the signals of hunger to the brain. This receptor is a part of our neurological
system. This way a smooth coordination is established between our brain
and digestive system. Whenever, there is some unbalancing in the functioning
of the CB-1 receptor, a person can start eating excessive food.
The launch
of this drug is anticipated in many other countries; Germany, Denmark,
Norway, Ireland and Finland are the prominent among those countries.
FDA approval for Acomplia is in the line only after that the drug will
be launched in the US anti-obesity drug market most probably by the
name of Zimulti. Sanofi-Aventis is highly anticipative to get approval
soon.Rimonabant is approved by European union for sale and is being
sold in the United Kingdom by Sanofi-aventis under the trade name Acomplia.
FDA approval has been delayed until the second half of 2006. If you
take this weight loss drug, Acomplia (Rimonabant), you will automatically
eat less because your hunger will be turned off. And when you start
losing weight, the first place you will lose body fat is your mid-section.
The pounds will just melt away. And better yet, your cholesterol will
go down and your blood pressure will return to healthy levels. Acomplia
Rimonabant (Zimulti in the USA) is recommend to those patients (BMI
= 30 kg/m2), or overweight patients (BMI > 27 kg/m2) with associated
risk factors such as type 2 diabetes or dyslipidemia. Acomplia also
has been studied by Sanofi-Aventis as an aid to smoking cessation based
on studies for up to one year in over 6,500 smokers motivated to quit
smoking.
How
Acomplia really works?
Acomplia
is an oral prescription medication to treat obesity. It woks on the
principle of blocking the CB-1 receptors situated in the Endo-cannabinoid
system. These CB-1 receptors are responsible for regulation of food
intake in the body. Consumption of Acomplia primarily blocks the functioning
of these receptors, resulting in a decrease of your normal appetite.
A reduced appetite means that you would eat less, and in turn loose
weight. Acomplia, the oral prescription diet pill can help in such a
situation by inhibiting the functioning of CB-1 receptor. The active
constituent of Acomplia is Rimonabant which have the tendency of blocking
CB-1 receptor. Initially Rimonabant was clinically tested by Sanofi-Aventis
as an anti-smoking drug because the same CB-1 receptor is also responsible
for carrying the signal of urge for smoking to the brain. During this
testing Acomplia (Rimonabant) is found very effective in curbing enormous
urge for food. After rigorous clinical tests the drug manufacturer Sanofi-Aventis
launched Acomplia in the UK anti-obesity drug market in the month of
June. The popularity of drug among the people of the UK is a proof of
its efficacy.
In the
second study (the RIO-Lipids study,) 1036 patients who were either overweight
or obese and who had blood lipid disorderswere also randomized to one
of three groups (placebo vs. 5 mg/day or 20 mg/day rimonabant). After
1 year of treatment, patients receiving 20 mg rimonabant lost an average
of about 20 pounds of weight, compared to 5 pounds for patients on placebo.
Further, patients receiving 20 mg rimonabant had significant improvements
(compared to placebo) in waist circumference, HDL levels, triglyceride
levels, CRP levels, and insulin sensitivity. For patients with metabolic
syndrome at baseline (which included about 50% of the study population),
half of those taking 20 mg rimonabant no longer had metabolic syndromeat
the end of the study.
What
is Acomplia used for?
It is an
ideal solution for people who have BMI greater than 30. BMI refers to
Body Mass Index, which is a calculated value of body weight in proportion
to height. Rimonabant pill is like a magic potion, which can facilitate
you to make an easy escape from the clutch of obesity and its consequent
health problems.
Besides, serving as a weight loss pill it can also curb the unhealthy
craving of smoking. Its benefits also include improvement in cholesterol
and other metabolic related health issues
Can
Acomplia help people quit smoking?
Data from
two studies with rimonabant were reported. In the first, called the
Stratus-US study, the drug’s effect on smoking cessation was evaluated.
In the study, 787 smokers (average of 23 cigarettes per day) were randomized
to receive either placebo, or rimonabant in doses of either 5 mg or
20 mg per day. The patients received the study drugs for 10 weeks. They
were permitted to continue smoking for the first 2 weeks, but were instructed
to attempt to quit smoking on Day 15. The number of patients who had
not smoked during the last 4 weeks of the 10 week period were tabulated.
Of patients who took 20 mg of rimonabant, 36% had quit smoking. Of patients
who took either placebo or 5 mg rimonabant, only 20% successfully quit.
Further, of those patients who quit smoking, the ones taking either
placebo or 5 mg rimonabant gained 84% more weight than those taking
20 mg rimonabant. Thus, rimonabant at 20 mg per day significantly increased
the rate of successfully quitting smoking, and also greatly reduced
post-smoking-cessation weight gain
Acomplia
recomandation
Persons
with heart diseases, lung diseases, allergy, diabetes, hypertension
and blood pressure etc. should take proper attention before taking Acomplia
diet pills. Women with pregnancy and breast feed child should also consult
a doctor.
Acomplia
side effects
Acomplia
may have some initial mild side-effects in some people like constipation,
stomach disorder, nausea, dizziness, anxiety and headache. However these
side effects are mild generally disappear with continuous use of the
drug for few days. Pregnant ladies and breast feeding mothers must avoid
using Acomplia.
Doctor’s
prescription and advice for starting the use of Acomplia is essential.
Both prescription and advice for Acomplia are available through online
pharmacies. They may or may not charge for their service; confirm this
thing beforehand.
In conclusion
as the scientists proved, rimonabant is the future for obesity treatment
and for quiting smoking. If you are looking for a helping hand in your
fight with fat rimonabant is could be a solution for you. I advise you
though to talk to a weight loss specialist or with your doctor before
purchasing rimonabant.
Acomplia
Side Effects Is it True?
Acomplia
the first diet pill that revolutionized the weight loss treatments is
well known in our days for it’s miraculous results. Nowadays obesity
is a huge problem for our health. More and more people are obese. This
is because we do not take care of what we eat, we eat more and more
unhealthy food every day, with allot of calories, high in fats and the
list can continue. Now the helping hand that acomplia can give for obese
people who want to follow a treatment with acomplia is that it blocks
the center of the brain responsible with the appetite.
As I said
in one of my previous article where I told you some tips on how to minimize
the effects of the changes that it will happen when following a rimonabant
acomplia weight loss treatment, the “side effects” are normal
and actually the same without any help from a diet pill. The difference
is that acomplia accelerates the effect of the diet and that is why
you feel the side effects more harsher. You can minimize them by eating
more fruits and drink more orange, lemon or grapefruit juice, do exercices
and take long relaxing walks in parks or somewhere in nature.
Something
to take into consideration when taking acomplia
It was
said at one moment that one of acomplia side effects was depression.
Studies showed that this kind of side effects appear only for persons
that have been taking some prescription antidepressants drugs in the
passed and have some mental instabilities. Also acomplia (rimonabant)
is not recommended for teens under 21 years old. The reason behind this
is that the brain is still under development until the age of 21 and
by blocking certain brain centers could lead to some unpleasant long
term side effects.
Do not
take rimonabant with alcohol! I insist on it because many people are
saying so what, if i take pills the worst thing that will happen is
that they will not have any effect. They are wrong. Mixing acomplia
(rimonabant), or any other diet, erectile dysfunciton or whatever other
pill, with alcohol can get you to the hospital with bad liver and stomach
damage.
DO NOT
OVERDOSE. Always respect the prescription that the doctor or a weight
loss specialist gave you. You will not obtain any quick results if you
take more pills. That will intoxicate your body and you will end up
in the hospital with bad liver damage or worse brain damage, or even
worse.
Take this
into consideration when dieting with acomplia (rimonabant), and with
hope that this will help you in your fight against obesity i wish you
good luck and belive in what I say: you will have a smile on your face
each time when you look in the mirror if you respect the diet properly
and consult your weight loss specialist each time you encounter a problem.
Inches
Dropped From Waistline
Participants
in the study were randomly selected to take either low-dose Acomplia
(5 mg), high-dose Acomplia (20 mg), or a placebo. Additionally, all
patients were told to reduce their daily caloric intake by 600 calories.
They were not given any specific dietary guidelines, nor were they given
exercise recommendations.
After two
years, the patients taking 20 mg lost an average of 16 pounds and kept
the weight off. The patients taking lower dose Acomplia lost an average
of 10 pounds. Patients taking a placebo lost an average of 5.5 pounds.
Perhaps
even more encouraging, says Van Gaal, is that the patients taking Acomplia
dropped inches from their waist, which is especially significant since
expanding waistlines are associated with increased risk of heart disease
and diabetes.
Van Gaal
says that it looks like each 2.2 pounds of weight lost takes an inch
off the waist. The average waist reduction was 3 inches for patients
taking 20 mg and 1.3 inches for those on the lower dose.
After the
first year of treatment, 39% of patients taking high-dose Acomplia were
able to reach a goal of losing 10% of their weight. After two years,
32% of the high-dose patients maintained that level of weight loss.
This is
very encouraging, says Van Gaal, because “people always say they
want to lose 40 pounds, but you can achieve real health benefits by
losing 10% of your body weight. This is a realistic and sustainable
goal.” He says other studies have reported that patients who hit
the 10% goal cut their risk of developing diabetes in half.
